covid-19 vaccine guidelines india

 COVID-19 vaccine related GK Question

1 -COVID-19 vaccine is scheduled for roll-out in india - 16th January 2021

TYPE Covid-19 vaccines, under Indian Government supply 

1.COVISHIELD 

2. COVAXIN

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Precautions se related point

  •  Authorized Age Group - 18 years and above

  •  Co-administration of vaccines- no, : If required, COVID-19 vaccine and other vaccines  should be separated by an interval of at least 14 days

  •  Second dose  Interchangeability of COVID-19 Vaccines - not permitted (Second dose should  also be of the same COVID-19 vaccine which was administered as the first dose)

Special precautions: 

  • Vaccine should be administered with caution in persons with a history of any bleeding or coagulation disorder (e.g., clotting factor deficiency, coagulopathy or platelet disorder). 


Contraindications for COVID-19 Vaccination 

Persons with history of: 

  1.  Anaphylactic or allergic reaction to a previous dose of COVID-19 vaccine 

  •  Immediate or delayed-onset anaphylaxis or allergic reaction to vaccines or injectable therapies, pharmaceutical products, food-items etc. 

  1.  Pregnancy & Lactation: 

  • Pregnant & Lactating women have not been part of any COVID-19 vaccine clinical trial so far. Therefore, women who are pregnant or not sure of their pregnancy; and lactating women should not receive COVID-19 vaccine at this time 

Provisional / temporary contraindications: In these conditions, COVID vaccination is to be deferred for 4-8 weeks after recovery 

  •  Persons having active symptoms of SARS-CoV-2 infection. 

  •  SARS-COV-2 patients who have been given anti-SARS-CoV-2 monoclonal antibodies or convalescent plasma 

  •  Acutely unwell and hospitalized (with or without intensive care) patients due to any illness 


Following conditions are not contraindicated for COVID vaccines 

  • Persons with a past history of SARS-CoV-2 infection (sero-positivity) and or RT- PCR positive illness History of chronic diseases and morbidities (cardiac, neurological, pulmonary, metabolic, renal, malignancies) Immuno-deficiency, HIV, patients on immune-suppression due to any condition (the response to the COVID 19 vaccines may be less in these individuals) 


Type of Vaccine

  1. COVISHIELD

  • Recombinant COVID-19 vaccine based on Viral Vector Technology 

  • No. of doses in each vial -10

  •  Shelf life -6 months 

  • Route -Intramuscular (IM) Injectable

  • Dose -0.5 ml each dose 

  •  Course -2-doses 

  •  Schedule - 4-weeks apart 

  •  Expiry date available on vial-  Yes 

  •  Vaccine Vial Monitor (VVM)-  Not Available 

  • Physical Appearance Vaccine- Clear to slightly opaque, colourless Vaccine  to slightly brown 

  • Vaccination during Pregnancy - Not recommended 

  • Vaccination < 18 years - age Not recommended 

  • Vaccination to Lactating- Not recommended  mother 

  • Storage and transportation -   +2°C to +8°C at all levels 

  • Not applicable Open Vial Policy 

  •  Freeze Sensitive - Yes (Discard the vaccine vial, if “frozen’ or “frozen and thawed'

  •  found Discard the vial, if -Solution is discoloured or visible Presence of particulate observed

  • Some mild AEFI may occur like-injection site tenderness, injection site pain, headache, fatigue,  headache myalgia,  malaise, pyrexia, chills and dizziness-giddiness, tremor, sweating, cold, arthralgia, nausea 

  • Paracetamol may be used to provide symptomatic relief from post vaccination adverse reactions 

 intramuscular injections, COVISHIELD should be given with caution to individuals with thrombocytopenia

2. COVAXIN

  • Whole-Virion Inactivated Corona Virus

  • No. of doses in each vial -20

  •  Shelf life -6 months 

  • Route -Intramuscular (IM) Injectable

  • Dose -0.5 ml each dose 

  •  Course -2-doses 

  •  Schedule - 4-weeks apart 

  •  Expiry date available on vial-  Yes 

  •  Vaccine Vial Monitor (VVM)-  Not Available 

  • Physical Appearance Vaccine- whitish translucent

  • Vaccination during Pregnancy - Not recommended 

  • Vaccination < 18 years - age Not recommended 

  • Vaccination to Lactating- Not recommended  mother 

  • Storage and transportation -   +2°C to +8°C at all levels 

  • Not applicable Open Vial Policy 

  •  Freeze Sensitive - Yes (Discard the vaccine vial, if “frozen’ or “frozen and thawed'

  •  found Discard the vial, - if Presence of particulate matter or coloration

  • Some mild AEFI may occur like -  injection site pain, headache, fatigue, fever, body ache, abdominal pain, nausea and vomiting,dizziness-giddiness, tremor, sweating, cold,cough and injection site swelling

  •  Shake well, before use 

  • Use of Chloroquine and Corticosteroids may impair antibody response. 



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