gynecology and obstetrics notes pdf / OBG notes PDF download

 Obstetric and Gynecology Short notes

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Instruments used in delivery 

1. Trocar-Insert into abdomen cavity for laparoscopy 
2. Uterine sound - Measuring the length of uterocervical canal 
3. Bladder sound - Use for cystocele 
4. Ethylone - Non absorbable synthetic suture
5.Catgut suture - Absorbable suture (7days)Made by sheep intestine
6.Spounge holding for shape - to hold the gauss
7. Pinards fetoscope / fetoscope - Auscultation of heart sound
8. ovum holding forceps - To remove the product of Conception
9. Rubin's cannula - Device use for infertility
10. Karmans cannula - Use in abortion 
11. Kocher's forcep - To clamp the umbilical cord 
12. Hegar's dilator - For D & C 
13. Doyen's retractor - Use in contraction of bladder 
14. Babcock for shape - To hold the tubular structure
 15. Allis forcep - Hold the hard structure of body 
16. Ayre's spatula- For taking pap smear
 17. Artery forcep - Clamp the bleeding vessels 
18. Punch biopsy - Take the biopsy for cervical cancer and skin cancer 
19. Myoseizure- To cut the suture 
20. Mayotrolly - Trolly use for surgery
 21. Kelly's forcep - To control bleeding

External Genital (Vulva)

Anterior Structures :

  1.  Mons pubis (Mons veneris) :- At puberty Hair present 
  2. Perineum :-(Posterior part) (4x4)
  3.  Labia Majora (Homologous to scrotum)
  4.  Labia Minora :- Excessive nerve supply 
  5. Clitoris (Homologous to penis)
  6. Prepuea (Anterior to clitoris) 
  7.  Hymen :- Occluded-almost half by mucous membrane 
  8. Bartholin Gland :- Pea shape, yellowish white colour gland, during intercose secreate alkaline fluid 
  9. Skene's duct :- Act as female ejecullation 
  10. Vestibular bulb:-Homologos to corpus spongiosum + penis
Opening in Vestibule :
  • 2 ductal opening of bartholin gland 
  •  1 ductal opening of urethral opening 
  •  1 Vaginal opening
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Internal Organ

1.Vagina
  1. Vagina Fibromuscular Organ 
  2. Organ of copulation 
  3. Organ for passage of menstrual discharge 
  4. Birth Canal
  5.  Direction - Upward & backward 
  6. Anterior wall 7 cm, posterior wall -9 cm in length
  7. Vaginal Fornix-Space between veginal part of cirvix & veginal holl, Total - 4( Anterior, Posterior & 2 lateral) 
  8. PH:- Acidic (4-6, due to presence of doderlein bacilli (Lactobacillus acidophilus) The bacilli convert the glycogen into lactic acid 

2... Uterus :- Antiversion & anti flexion
  1. Devolpment- mulirine duct 
  2. Hollow muscular organ
  3.  Pyriform shape
  4.  Measurement 7.5x5x2.5 cm (Length : width: thickness) 
  5. 35x23x10 cm (during pregnancy) (full term)
  6. length : width : thickness 
  7.  Weigh-60 gm
  8. 900-1000 gm in pregnancy 
  9. Pregnant Uterus : Soft & elastic 
Parts of uterus 
  1.  Fundus (upper to Fallopian Tube) - It is a site for Implantation Implantation occurs at anterior or posterior site of fundus.
  2. Body (Corpus) :- 3.5 cm 
  3.  Isthmus :-(Narrow part)-0.5 cm
  4.  Cervix - 3 cm 
Layers :
1. Perimetrium : Outermost
2. Myometrium : Three layers of muscles-Outer-longitudinal, middle-Interlacing oblique, Inner-Circular layer of muscles 
  • Significance of Interlacing muscle layer: after delivery it cease the supply of blood to the uterus & prevent the PPH
  • ( Living Ligature:-Due to the 8 shape of interlacing muscle )
3. Endometrium: during pregnancy it has three layers
 I.Basai Layer- (regeneration of endometrium)
 II. Spongy Layer
  • It is the site of Placental Separation (Cleavage) 
 III.Compact Layer (Superficial) After Menstrual cycle Regeneration Start- at the Basal Layer 
  • Decidua :-(Endometrium of pregnant woman](Q)
  • It shed after delivery. 
Decidua may be classified into three layers
  1. Decidua Basalis :- Placenta attach to this site. 
  2. Decidua capsularis- Layer that surrounds the fetus (parietalis) 
  3. Decidua vera-remaining endometrium, lining uterine cavity

3. Fallopian tubes; Shalphinges (Uterine tube] 
 10 cm length 
Parts 
  1.  Interstitial/Intramural 1-1.25 cm
  2. Isthmus (narrow part) 2.5 cm 
  3. Ampulla (largest) 5 cm- site for Fertilization 
  4. Infundibulum:-1.25 cm continuous to the fimbriae 
Large ovarian fimbriae that transport ovum is ovarian fimbriae 

4. Ovary: -2 in number
  1.  Size-3x2x1 cm
  2. Shape - oval shape 
  3. Intraperitoneal organ 
  4. Function-Ovum or Sex hormone production (Mature follicles releases oestrogen harmone, Corpus leutium releases progesterone & oestrogen 
  5. Ovum: Largest cell of body (Pinkish gray colour )
Structure of Ovary 
1. Ovarian Cortex (Outer vital part): 
  • It is made of Stroma (connective tissue of the ovary) . 
  • Various sizes of follicles are present 
  • One mature follicle: Graffian follicle
2.  Medulla-inner structure, Blood Vessel present 
  • Mesovarium-Structure of ovary through which blood vessels & nerve enters in to ovary
  • Ligaments supporting to the ovary & uterus 
  • Round Ligament 
  • Broad Ligament 
  • Ovarian Ligament 
  • Present HILLUS CELLS (Homologos to interstitial space of tespis)
  • It resemble leydig cells

Ovarian Cycle
  1. GnRH (Gorado trophic Releasing hormone) secreted by hypothalamus & it stimulate the anterior pituitary gland to release
  2. FSH: It Mature the follicles 
  3. Oestrogen hormone released by growing follicles in ovary 
  4. Oestrogen act on a pituitary gland to release Luteinizing hormone 
  5. LH is responsible for ovulation. 
  6. One mature follicle rupture under the influence of LH & releases the ovum. The ruptured follicle becomes corpus luteum . Corpus luteum secretes progesterone: the hormone prepare the endometrium for Implantation 
  7. If pregnancy does not occur the corpus luteum converts into corpus albicans. 
  8. If fertilization occurs then up to 10-12 weeks oestrogen & progesterone released by corpus luteum.
  9. Pregnancy maintaining hormone-progesterone 

Menstrual Cycle 
1. Ovarian Phase: responsible hormones are Oestrogen & Progesterone. 
Ovarian phase -
  •  (a) Follicular phase-13 days  
  •  (b) Ovulation-on 14 days
  •  (c) Luteal phase-15-28 days
2. Uterine Phase (Menstrual Cycle)-LH, FSH & Pituitary Hormone are responsible. 
  • A. Menstrual Phase (4-6 days) 
  • B. Proliferative Phase (9-10 days)
  • C. Secretory Phase (14 days) 
Q.: The hormone responsible for Proliferative phase of menstrual cycle
ANSWER:  FSH & Oestrogen
  • Ovum viable (Life Span)-12-24 hrs.
  • Sperm Viability-48-72 hrs. 
  1. Amenorrhoea :- Absent of menstrual cycle
  2. Metrorragia:- Irregular menstrual cycle
  3. Menorragea :- Menstrual cycle more than 7 days or blood loss more than 80 ml
  4. Oligomenorrhea:- The interval more than 35 days 
  5. Hypomenorrhoea :- Blood loss less than 10 ml
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Female pelvis
Type of pelvis :
1. False Pelvis: - Part above pelvic brim
  • To support the gravid uterus 
2. True pelvis :- Lies below the brim 
According to shape type of pelvis :
01. Gynecoid pelvis :- Most favorable pelvis for delivery 
  • Round shape 
2. Anthropoid pelvis :- Antero-posterior oval shape 
3. Android pelvis :- Heart / triangular / wedge shape Male pelvis 
4. Platypoid :- transverse oval shape  / flat / kidney
shape Angle of inclination :- In erect position female pelvis make 55 /135° angle 
Diameter of pelvis :
Antero-Posterior Diameter of intent :
1. True conguitate - Upper part of SP. to midpoint sacral promontory 
2. Obstetrical conjugate - Mid point of SP to midpoint of sacral promontory 
3. Diagonal conjugate - Lower part of SP to midpoint of sacral promontory 
Weste space of morris :-Distance between symphysis pubis & circumference disk
  • normal less than 1 cm 
Contracted pelvis :- Variation in shape and size of normal pelvis 
Type of Contracted pelvis
1 :Rachitic pelvis- increased transverse diameter and decreased A-P diameter
2.  Kyphotic Pelvis - Excessive funneling pelvis
3.  Negeale’s Pelvis - arrest the development of one side ala of sacrum
4  Robert's Pelvis - Both side aia note develop

Suture of fetal skull :- 
1. Frontal suture- Between two frontal bone
2. Sagittal suture- Between two parietal bone
3. Lambdoidal suture- In between parietal and occipital bone
4.Squmus suture - Between parietal and temporal bone 
5. Coronal suture-Between frontal and parietal tone

A-P Diameter of fetal skull
1. Sub-occipto bragmatic :- most commonly engaging diameter 
  • Fully flexed  /universal diameter 
  • Center of brahma to nape of neck
  • Length - 9.5 cm 
2. Sub-occipto frontal :- 10cm
  • Extend anterior end of brahma to nape of neck 
3. Occipito frontal :- 11.5 cm
  • Extend glabella to occipital eminence
4. Mentovertical :- 14 cm
  •  Highest diameter 
  • Extend mid point of chin to highest point of sagittal suture 
5. Sub-mentovertical :- 11.5 cm 
  • Extend junction of floor to highest point of sagittal suture
6. Sub-mentobragmatic - 9 cm
Extend Junction of floor to center of brahma 
  1. Bipiratal diameter (9.5 cm):-Space between two parietal eminence
  •  Most common engagement diameter 
  1. Supper sub-piratal diameter :- 8.5 cm
  2. By temporal diameter :-8 cm 
  3.  By mestoied diameter :- 7.5 cm 
Fertilization
  1. Fertilized ovum reach in uterus (fundus) in 6 days (from ampulla to uterus) Implantation (Nidation)-11th day of fertilization Zygote (Interstitial implantation)
  2. Blastomere (2 cell structure)
  3. Morula (16 cell structure)
  4. Blastocyst (64 cell structure) 
  5. 12th day chorionic villi start to form Primary villi - (12-13 days) 
  6. Secondary villi- (16 days) 
  7. Tertiary villi - (at 21 days) (Feto placental circulation starts) 
  8. Hartman's sign :- bleeding during implantation

Placenta
  1.  Placenta is made of Chorionic Frondosum & Decidua basalis 
  2. Fetal part of placenta is =5/6 part 
  3. Maternal part is = 1/6 part 
  4. It is 1/6 (500 gm) of newborn's body weight.
  5. Complete formation of placenta occurs at 12 weeks.
 Another name of placenta: - Deciduate-Because it shed at the time of delivery.
  1.  Hoemochorian-Because it is in direct contact of maternal blood 
  2.  Discoid-Because of its shape Functions of placenta:
Function of placenta
  •  Respiratory organ
  •  Excretory organ  
  • Nutritive organ 
Structure of placenta:
  • Maternal Surface 
  •  Fetal surface (shiny, jelly)
  • 15-20 Cotyledons (1 cotyledons =4-5 major steam villy) 
  • (Rough, dark, projection) 
Nursing responsibility: Significant to watch cotyledons after delivery of placenta & PPH diagnosis. 
  • Blood volume in placenta - 500 ml (350 ml villus space and 150 ml intervillous space)
  • Phagocytic cells of placenta - hofbaur cell
Pressure of fetal and maternal artery :
  • Maternal artery - 70-80 mm/hg
  •  Maternal vein - 8 mm/hg
  • Fetal artery- 60 mm/hg
  •  Fetal vein - 10 mm/hg 
Pressure of intervillous space -
  • During contraction - 30-50 mm/hg
  • During relaxation - 10-15 mm/hg 
Placenta bariour :
  • Syncytiotrophoblast (outer)
  • Cytotrophoblast
  •  Basement membrane 
  • Stronal tissue 
  • Endothelium of fetal capillary

Two zone of syncytiotrophoblast 
I a-zone (Thin) - Gas exchange
2. B-zone (Thick) - Hormones synthesis 
Abnormality of placenta - 
1. Placenta succenturiata :- A part of the lobe of the placenta is situated away from the margin of main placenta & communicating blood vessels present between both parts.
  • Complication - PPH 
 2. Plasenta spuria :- No connection of blood vessels
3. Placenta extrachorialis :
  • A. Circumvallate placenta - chorionic plate of placenta is smaller than basal plate 
  • B. Placenta marginata - Chorionic plate of placenta is larger than basal plate
  • Complication - abortion 
4. Placenta membrancia :- Large and thin placenta which covers whole embryo
  • Complication-Growth retardation 
Placenta Accreta :- Normal attachment of placenta 
5. Placenta Increata :- chorionic villi invade into myometrium 
6. Placenta percreta :- chorionic villi invade throw the myometrium Complication- PPH 
7. Placenta reflexa :- Placenta margin's are thick & centre are thin
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Umbilical cords (Funis)
  1. Develop from body stalk
  2.  Covered by Wharton's jelly 
  3. Length-50 cm. 
  4. Diameter:-1.5 cm 
  5. First trimester (2 artery + 2vein) 
  6. at 4th month (2 A +2 vein) 
  7. At birth: 2 A+ 1 vein
  8. IA+1V: Indicate Renal agenesis/Genital agenesis adverds syndrom (Overlapping of finger) 
  9. Oxygenated blood from mother to fetus is carried by umbilical vein, while Deoxygenated blood from fetus to mother is carried by umbilical artery.

 Abnormality of umbilical cord :
  • Battledore placenta - U. code attached to margins of placenta 
  •  Velamentous placenta -U. code attached to fetal membrane 
  • Short code - less than 20 cm
  • Long code - more than 200 cm 
  • Acordia - absent of U. code (Placenta directly attached to fetal liver)
Life Cycle 
  1. Ovulation occurs at 14 day before next menstruation.
  2.  Fertilized ovum: 0 to 2 weeks a Division start after 24 hrs.
  3. On 1st day 2 cells structure, Blastomere: 8 cells, Morula: 16 cells on 3rd day, Blastocyst (5th day) (64 cell)
  4. Time of blastocyst to reach the uterus-[6-7 days) o On 6 days after fertilization implantation start
  5. 10-11 day implantation complete 

Fetal membrane 
1. Chorion:Outer layer of fetal membrane ;develop from trophoblast;outer layer of blastocyst & Fussed to decidua vera & reflexa (cyto & syncytiotrophoblast)
  • Chorion contains no vessel & no nerve supply 
  •  Chorion fetal membrane secrete HCG 
2. Ammion:Inner layer No blood, nerve & lymphatic supply
  •  Function-formation of liquor amini
  • Amniotic fluid Volume of amniotic fluid 
  • 12 wks - 50 ml
  • 20 wks - 400 ml 
  • 38 wks - 1000 ml 
  • 40 wks - 600-800 ml
  • 43 wks - 200 ml 
  • Daily production of amniotic fluid=400 ml 
Specific indicator of amniotic fluid
  • Post term(42 wks): amniotic fluid, saffron colour (Greenish yellow) 
  • Fetal distress (Meconium aspiration Syndrome) Green colour
  • Golden color: Rh Incompatibility 
  • Tobacco Juice(Dark Brownish color): IUD 
  • Dark color: Concealed Haemorrhage 
  • Amniotic fluid-slightly alkaline 
  • Specific gravity =1.010 
  • Osmolality: 250 mili Osmol/ liter 
Examination of amniotic fluid : 
  1. To examine fetal maturity
  2.  To identify any congenital malformations 
Fern test -
  • To determine leakage of amniotic fluid. 
  • Specimen of vagina Test (Fern Like Pattern) + Present → Amniotic fluid + Present.
Position - Dorsal recumbent position.
Instruct Client to cough 
Nitrazine test -
  • To check presence of amniotic fluid in Vaginal secretion 
  • If Amniotic Fluid present in vaginal discharge: Nitrazine strip changes to blue.
Position - Dorsal recumbent position. 
Amniotic fluid embolism -Amniotic fluid enters in maternal circulation & deposits in pulmonary arterioles. 
C/M - Chest pain & Respiratory distress.
Fetal bradycardia & distress. 
Fetal distress, Prepare client for emergency C.S. 
Supine hypotension
 Place a pillow or wedge under the client's right hip
Fetal circulation
  • Ductus venosus :- Connection between umbilical vein and IVC 
  • Functional close - Just after birth (within few minute)
  • Anatomical close - 7 days after birth 
  • 7 days after changed ligamentum venosum
  •  Ductus arteriosus :-Connection between pulmonary artery and aorta 
  • Functional close up just after birth 
  •  Anatomical close (1-3 month change ligamentum arteriosum 
  • Foramen oval :- Connection between right atrium and left atrium 
  • Functional close - just after birth 
  • Anatomical close- 1 year after change -Fossa ovalis 
Pregnancy & its terminology
  •  Reproductive age begins with the age:13-15
  • years Safe pregnancy : 20-35 year
  • High risk pregnancy : < 20 year and > 35 year 
  •  Nullipara-No baby delivered 
  • Duration of Pregnancy: 
  •  Should be calculated from Ist day of LMP
  • Fertilization or ovulatory age-(Accurate period)
  • 280-14 = 266 days 
  •  Gestational Period- 9 Calendar Month/10 Lunar Month /40 weeks/280 days 
  • Negales formula : EDD = L.M.P. + 9 month + 7 days 
  • Gradiva-No. of pregnancy 
  • Parity / Para-No.of delivery after viability (>20 Weeks) either alive/dead(still birth) 
  • If Twin pregnancy is there then Para-1, Gravida-1
  • Abortion-Expell the product of conception before 20 weeks. 
  •  Primipara mother : One baby delivered
  • Primigravida: First time conceived
  • Grand Gravida-more than 4 timos conceivement. 
 Parity - No. of birth past 20 weeks of gestation (After viability). 
  •  G- Gravidity (No. of pregnancies)
  • T- Term birth (> 37 week) 
  • P- Preterm birth (< 37 week)
  • A- Abortion 
  •  L-Live children. 
Division of duration of pregnancy:
  • First trimester for (0-12 weeks); 12 wks.
  •  II trimester for (13-28 weeks); 16 wks.
  •  III trimester for (29-40 weeks); 12 wks.
  • First trimester weight gain-1 kg. 
  •  II trimester weight gain- 5 kg
  • III trimester weight gain-5 kg

Antenatal Examinations Four Grip
Stand-right side of the patient 
  1.  Fundal grip- assess lie, presentation 
  2.  Lateral grip-(umbilical grip)-fetus in left or right side 
  3.  First pelvic grip-Leopold's IVth maneuver assess Engagement & presenting part 
  4.  Ilnd pelvic grip-Leopold's IIIrd grip / Pawlic grip-assess convergence & divergence 
Non Stress Test
Reactive NST (Normal, Negative)
  •  FHR acceleration of 15 bpm for 15 sec. in 20min. Observestion. 
Non reactive (Abnormal)- No acceleration or <15 bpm 
  • (Positive.) in < 15 sec for 40 min. observation

Contraction Stress test :
To check placental O, & function. (Oxytocin Given to stimulate contraction). 
Negative (Normal) - No late deceleration of FHR 
Positive (Abnormal) - No late deceleration of FHR with 50% or more of contraction in absence of hyperstimulation of the uterus.
Sign of pregnancy
Positive sign of pregnancy
  •  FHS 
  •  Active fetal movement by examiner
  • Sonography finding
 Probable 
  •  Ballottement
  • Braxton Hicks contraction 
  • Enlargement of uterus Presence of HCG in urine quickening 
  • Chedwick's sign (Jacquemier sign) -Bluish discolouration of vagina (8 wks.)
  • Goodell's sign - Softening of cervix (6 week)
  •  Hegar's sign- Softening of lower uterus (6-10 weeks)
  • Osiander sign- (Pulsation Feel at lateral fornix) (8 week) 
  • Palmer sign -Regular & rhythmic utérine contraction during bimanual examination of mother(4-8 weeks
  •  Dark pigmentation of skin : Chloasma 
Presumptive 
  •  Mother feeling
  • Morning sickness 
  •  Quickening
  • Lighting
  • Amenorrhoea 
Subjective changes
1. Amenorrhoea 2. Nausea & vomiting 3. Fatigue, anorexia 4. Frequency of urine
Breast discomfort & heaviness 6. Heartburn(Pyrosis) 
Objective changes
  •  FHS by doppler method can be heard at 10 weeks 
  • Presence of Montgomery tubercles at breast 
  • Upper part of the uterus is enlarged by the growing fetus. 
  • Lower part of the body is empty & soft.
Changes during second trimester of pregnancy
  •  (13-28 weeks, IInd Trimester Weight.gain : 5kg) 
  •  Amenorrhoea
  • Cutaneous changes (hyperpigmentation) 
  • Cloasma gravidarum (face mask) (pigmentation of cheek, forehead) 
  • Linea nigra (dark line from xiphoid process to pubis ) 
  • External ballotment -10-12 weeks
  • FHS (18-20 weeks) by fetoscope 
  • Quickening-18 weeks 
  • Palpation of fetal parts-20 weeks
  • Braxton Hicks contraction

 III Trimester:- 29-40 weeks. Wt. gain-5 kg.
  • Cutaneous Change more prominent 
  • Amenorrhea continue 
  • Fundal height - increases
  • Lightening occurs at 36 to 38 weeks 
  •  Frequency of urination 
 In pregnancy Nausea, vomiting-Due to HCG.
In pregnancy constipation, heartburn, flatulenceDue to progesterone. 
To prevent heartburn-Sitting upright for 30min after meal.In pregnancy gum bleeding, ptyalism (Excessive salivation)-due to Estrogen. Total weight gain = 1 +5+5 = 11 kg,
IV Trimester-Puerperium; Duration : 42 days

Reproductive part of weight gain:5.5 kg 
  •  Fetus- 2.5-3 kg
  • Placenta- 0.5 kg
  • Amniotic Fluid-800-1000 ml, ( Uterus- 1 kg 
Maternal part of weight gain:5.5 kg
  • Volume-2-2.5 litre
  • Blood 1-1.5 L 
  •  Intracellular 1-1.5 Lir
  • Deposition of fat (3-3.5 kg) 
  • Breast-400 gm " 
  • Mammogenesis-Enlargement of mammary gland
  • Lactogenesis-Production of milk
  • Galactokinesis-Ejection of milk 
  • Galactopoiesis-Maintenance of Lactation 
Uterus Size & shape during pregnancy
  • Pyriform-Non pregnant  
  • Globular-at 12 wks
  • Hen's egg-6 weeks.
  • Cricket ball-8 weeks. 
  • Fetal head-12 weeks. (into pelvic cavity)
  • Uterus B/w symphysis pubis & Umbilicus-16 weeks  
  • Fundus at umbilicus in 22-24 weeks. 
  • Maximum fundal height-36 weeks.  xiphoid process " 
  • Length: 36 cm; symphysis pubis to xiphoid process. 
  • At 38 weeks lightning of fetal Head occurs & uterine length becomes equal to 32 weeks.
  •  If Head flot; the gestational period is 32 weeks "
  •  If head fixed - 40 weeks
Embryonic development
  1. At  3 week-heart begins to beat.
  2.  The heartbeat is detected by a doppler transducer --b/w 10 to 12 week. 
  3.  Heart beat detected by fetoscope at 20 week. 
  4. At 24 week-Fetus has the ability to hear. 
  5. At 28 week (L/S forms) & lungs are developed sufficiently to provide gas exchange. 
  6. At 32 week-L/S ratio 1.2: 1. 
  7. At 36 week-L/S ratio > 2:1. 
  8. FHR (In I trimester) 160 to 170 bpm. 
  9. FHR (In II & III trimester) 120-160 bpm. 
(at term) Lie is the relationship b/w fetal & maternal axis 
  • (it is a relationship between fetal spine & maternal spine)
  • Commonest Lie-Longitudinal 
Presentation : Part of fetus that occupy the lower uterine segment. 
  • a Breech: Podalic
  • Commonest-Cephalic-(Vertex, face) 
  • Presenting part : Part that comes to contact with the pelvic floor. 
Attitude :- Relationship of fetal body parts to each other
  • common attitude -flexion attitude
position
  1. Fundal height of mother is measured  Dorsal recumbent position 
  2. Sim's-Catheterization, Card prolapse (b) 
  3. Lithotomy-Delivery
  4. L. Lateral-enema, before Liver biopsy, 
  5. R. Lateral-after liver biopsy  
  6. Trendelenberg - pelvic surgery, hypotension : Abruptio placenta 
  7. Prone-neural tube defect (Pre & post operat)
  8. Cardiac-Cardiac Pt. asthma 
  9. Knee chest-TOF, cord prolapse 
Puerperium :
  1. Duration: 42 days(6 weeks) 
  2. IV Trimester of pregnancy
  3.  6 Weeks after delivery
 Minimum Recommended antenatal visits - 4
  1. Ist visit should be advised at 16 weeks 
  2. IInd visit - 24 weeks
  3. IIIrd visit - 28 weeks
  4. IVth visit - 36 weeks 
Ideal visits : 
  • Up to 28 weeks. Once in each month: total -7
  • 8, 9 months in every 15 day; Total - 4
  • After 9 month-one in each week Most common time of delivery
  • 2 week before EDD or 1 week after EDD 
Investigations in First antenatal visit
  • History, Physical Examination, Urine, Blood-Hb,Height, B.P.
Advise in antenatal period:
Nutrition :
  1. Pregnancy + 300 cal 
  2. Lactation: + 500 to 600 cal
  3. Supplement : IFA 
  4. Folic acid-prevent neural tube. Folic acid is given to a woman before pregnancy. 
  5. Folic acid should be started at least 2 months before pregnancy & up to 3 months after pregnancy Doses : 0.4 mg/day 
  6. Iron : One Tab.- 60 mg elemental iron 
Q.: What diet a nurse will advice to a pregnant having hyperemesis gravidarum 
Ans. Biscuit & Toast with tea, milk before bed Not fatty food should be given 

Vaccination :
  1.  TT at Deltoid muscle
  2. Ist dose, 0.5 ml as soon as pregnancy diagnosed; 
  3. Ilnd dose : 4 weeks after first dose
  •  Live vaccines should be avoided during the antenatal period because viruses may cross the placenta.
Minor Element of pregnancy
  1. Nausea/Vomiting :-Due to HCG 
  2. Constipation :- due to progesterone
  3. Heartburn (Pyrosis)- due to projectrone 
  4. Ptyalism - due to oestrogen
  5.  Excess vomiting in pregnancy-Hyperemesis gravidarum 
Rubella Vaccine :
  • If client has titer (< 1:8), Susceptible to rubella, give vaccine in postpartum period. Advised for not becoming pregnant up to 1-3 month of Immunization. 
  • Avoid contact with Immunocompromised people. 
  • Not give  Rho (D) Ig, bcoz it reduces effectiveness of rubella vaccine.
  • Rubella-live attenuated virus- So do not give during pregnancy, It crosses placenta & risky for fetus. 
To detect syphilis :
  • VDRL (Venereal Disease Research Laboratory) 
  • RPR (Rapid Plasma Reagine) Test. 
  • USG/Chorionic villus sampling/Amniocentesis (Before 20 week)
  •  In all these, drink water before the test to distend the bladder, to obtain a better Image of the fetus.
  •  Informed Consent should be taken before above said sampling 
  • Position during Amniocentesis: supine. 
  • After Amniocentesis Position: left Side
  • Complication of Amniocentesis - Amniotic fluid Embolism 
  • After CVS & amniocentesis; If chills, fever, bleeding, leakage at needle site, ved fetal movement, cramping occurs = Notify the physician. 
 Kleihauer Betke test
  • It is done to detect presence or fetal blood in maternal circulation & to Identify for need of
  • additional Rho (D) Ig in Rh negative mothers. 
Antenatal examinations :' 
  • Chorionic Villus Sampling : 10-12th weeks
  • Amniocentesis !4-16 weeks
  • Cordocentesis 18-20 weeks 
Serum AFP (Alpha fetoprotein):To diagnose
  • Trisomy of 21 Chromosome
  •  NTD
  • Down syndrome- Advice the antenatal mother for triple test 
  • Triple Test :AFP + HCG+Unconjugated oestriol

Treat the TORCH infections in pregnancy
  • T - Toxoplasmosis 
  • O - Others-Syphilis VDRL, STD 
  • R- Rubella C-Cytomegalo Virus (congenital cardiac defects)
  • H - Herpes 
Trichomoniasis :
  •  (Trichomonas Vaginalis) 
  •  Yellowish to greenish, frothy, mucopurulent,copious, malodorous vaginal discharge. 
Bacterial Vaginosis :
  • (Haemophilus Vaginalis). 
  •  Fishy odour of vaginal secretion. 
Vaginal candidiasis :
  • (Candida Albicans) 
  • White, lumpy, cottage cheese-like discharge by vagina. .

Intranatal period
Normal Labour (Eutocia): Product of conception comes out through Vagina. 
  • Precipitated labour -very fast process; labor completes within 3 hours Delivery: product of conception Comes out either vaginally or Cesarean 
  • Dystocia: Abnormal labor
  • Labour Pain: may be True / Fals 
  • Show :- Vaginal Cervical discharge + Blood 

Phases of Labour
Ist Phase of labour
  • '1. Latent phase :- 1-4 cm cervical dilatation. 
  • 2. Active phase :- 4-7 cm cervical dilatation 
  • 3. Transient phase :- 7-10 cm cervical dilatation 
  • Duration :- Primi-12 hours. 
  • Multipara:- 6 hours, 
  • First phase begins with Onset of true labour pain and ends to complete cervical dilatation 
  •  Partograph should be maintained in first stage of labour, 
  • Changes during first phase
  • Pain
  • Braxtan Hick contraction 
  •  Cervical dilatation & effacement 

IInd Phase :
  • It begins with Complete Cervical Dilatation to expulsion of fetus
  • Primi-2 hour, * Multi-30 minutes
 IIIrd phase- Expulsion of fetus to placenta removal
  • Duration: 15 minutes to 30 minutes 
IVth Phase Observation  after delivery of placenta. 
Management during first stage
  • Maintaining Partograph: It is described by Friedman (1954) 
  • Partograph Detect
  • 1. Cervical Dilatation 
  • 2. Descent of Head (Station) Range :- 5 to +5
  • 0 = Fetal head is to the level of ischial spine
  • -1, -2, -3 above the Ischial Spine. 
  •  +-below Ischial Spine. 
  •  Cervical dilatation measured with finger & written in centimeter f One finger = 1.25 cm dilatation
 Ilnd Phase of Labour : Mechanism of labour
  • Step-I : Engagement (in Brim)-at 38 weeks. Biparietal suboccipitobregmatic 
  • Step-II : Descent 
  • Step-III : Flexion 
  • Step-IV : Internal rotation-90° (2/8 Angle) 
  • Step-V : Extension : Phase in which Head Delivered 
  • Step-VI : Restitution : head rotate 45° opposite to internal rotation (1/8 Angie) 
  • Step-VII : External Rotation: head rotate 45 opposite to internal rotation
  • Step-VIII : Expulsion: laterally 
  • Nesting :- Sudden burst of energy in mother before 24-48 hour of labour. :

Management of IInd phase :
Positioning: Lithotomy
Clean with dry Prewarm towel 
Take APGAR score: I minute apgar score, 
  • Ind at the 5 minute
  •  Minimum score - 0 
  • Maximum score-10 
  • Score: 7-10 =Normal 
  • 4-6 = Birth Asphyxia
  • 0-3 = Severe asphyxia 
Clamping of Umbilical cord :
  • By Koecher's forceps. 
  • At 2 places first clamp 2.5 cm above the umbilicus, second clamp should be 2.5 cm above first. 
  • Keep in mind the 3C: Clean surface, Clean hand, Clean article 
Q.: Disease characterised by 3C 3 C - Cyanosis,Coughing Choking
 Ans: TEF

 Episiotomy
  • Procedure done in II phase of labour to facilitate the expulsion of the fetus. 
  • Provide perineal care using clean technique. 
  • Give sitz bath 
  • Apply Ice packs on perineum. 
  • Not apply vacuum suction device on head for > 25 min 
  • Amniotomy assists in Increasing Efficiency of contraction. 
  • After an anatomy assessment for the FHR pattern. 
  • During labour on fetal monitoring, if episodic acceleration present- Nurse's action Document finding because acceleration occurs with Contraction & Indicate fetal well being. Oxytocin Given during labour & if hypertonic Contraction occurs than Priority action
  • (1) Stop oxytocin, (2) Reposition client., (3) Check B.P., (4) Give 0, (8-10 L/min) by mask. (5) Perform vaginal Examination, (6) Give indication
  • to Uterine activity. 
Priority in umbilical cord prolapse:
  • (1) Elevate the fetal presenting part that is lying on the cord by applying fingers with a gloved hand. 
  • Give trendelenburg, modified sim's or Knee chest position
  •  Give oxygen (8 to 10 L/Min.)
  •  Monitor FHR
. IIIrd Stage (Placental separation) 
  •  After Placental Separation; Uterus becomesFirm (hard)
  Types of placental separation -
  1.   Central separation (Schultz)
  2.   Marginal separation (Methwe Dunken method) 
Nurse's Responsibility Inspect-cotyledon, if cotyledons are missed it can cause PPH
 IVth stage :
  • Liquid (Hot) should be given because mother may feel hunger
 Rooming in :
  • Mother & newborn should keep in close contact with each other.
  • Purpose-lactation 
Induction of labour :
  • Initiation of uterine contraction, give oxytocin.
  •  Stop oxytocin (Pitocin) Infusion if uterine contraction frequency < 2min. & duration > 90 sec. or If fetal distress present.
Lochia
  • Discharge upto 15 days 
  • Amouni : 250-350 ml 
  • Lochia Rubra - 0-4 day (RBC) 
  • Lochia Serosa- 5-9 day (Serous Fluid) 
  • Lochia Alba - 10-15 day (White-WBC) 
  • Duration of Lochia: Normal upto 3 week 
  • If > 3 weeks -Indicate infection 
  • Odour - Fishy smell
  •  Malodorous. Indicate Infection 
  • Ph: Alkaline
Involution
  • Reproductive organs return to the state of Pre pregnant Stage by retraction mechanism Most Crucial Phase - Phase III because of chance of PPH

Involution of uterus :
  • Uterus  Returns to a non-pregnant state. 
  • More fast in breast feed women bcoz oxytocin release 
  • 1 cm per day Involution occurs. 
  • By 10 day postpartum uterus can't palpated abdominally 
  • Flaccid Fundus: - Indicate atonicity (Massage fundus) 
  • Tender Fundus - Indicate Infection,
Postpartum complication
Cystitis :-- Infection of bladder.
  • Burning & pain on urination. 
  • increased Frequency of urination,
  • Costovertebral angle tenderness.
  •  Lower abdominal pain, fever
  • Obtain urine specimens for culture & Sensitivity before initiating antibiotic therapy.
  •  Priority Nsg. Action-Encourage fluid intake (3000 ml/day)
 
Hematoma :- Life threatening condition. 
Vulvar hematoma :Most common Apply Ice to reduce swelling 
  • C/M :- Abnormal severe pain & pressure in perineal area. 
  •  Bulging mass present, Inability to void.
  • decreased Hb value.
  • Sign of shock -decreased B.P., increase HR ., pallor
 Hemorrhage -
  • Bleeding > 500 ml. after delivery.
  •  In the Postpartum period, the primary cause of maternal mortality & require early intervention.
  • PPH :- Most common cause-Uterine atonicity. (Massage fundus to The tone of uterus)
  • Early sign- Restlessness. increased pulse rate. 
  •  Late sign -decrease B.P. 

Infection :- within 25 days of delivery.
  • S/S -Fever,increase temp > 100.4°F in 24 hour or after 24 hours 
  •  Chills, Anorexia, increased WBC.
  • Malodorous Vaginal discharge. 
  • Diet :- Nutritious, high calorie & high protein diet. 

Pulmonary embolism
  •  Due to thrombus in Uterine or Pelvic vein, DVT. 
  • S/S - Sudden dyspnoea & chest pain.
  • Tachypnoea & Tachycardia. 
  • Cough & lung crackles, Hemoptysis, 
  • Feeling of impending doom (Feel extremely bad is going to happen). 
Initial Nsg. Action - Give Oxygen 8-10 L/min, by facemask. 
  • Position :- Head Elevated. 
Thrombophlebitis :
  • Pelvic [Pulmonary embolism-I sing 
  • Superficial (TPRW) 
  • Femoral
  • Redness, pain, tenderness, warm 
  •  +ve Homan Sing S/S - Severechills or  increase body temp.
  •  Shrink white skin over the affected area. 
  • Heparin Sodium may be given to prevent further thrombus formation 
Intervention :
  •  Elevate affected leg.
  • Never massage  leg. 
  • Avoid leg crossing: prolonged sitting, constrictive clothing, pressure behind knee. 

Subinvolution :
  • A condition when reproductive organs do not return to their previous anatomical location & functioning or take a longer time to revert back. Uterus larger than expected. 
S/S :- Uterine pain on palpation, more vaginal bleeding 
  • Elevate legs to promote venous return. 
  • Give methergine for sustained contraction
  • Crowning = head visible at vaginal Orifice 
  • Retraction-Permanent shortening of muscle fiber. 
  • Contraction-Shortening of muscles fibers but not permanent
  • Moulding-overlapping headbone : Spontaneously disappear at 2-3 days

Bleeding in early pregnancy
  • (< 20 weeks)
  •  Causes may be 
1- Hydatidiform mole (vesicular mole): 
  • It is a benign growth of trophoblast type 
  • Tumor benign, may be malignant
  •  Grape like structures comes out through vagina, 
  • Bleeding per vagina -brownish 
Type :
                                       Complete                        Partial 
Embryo                             Absent                          Present
 Uterine size                       > pregnancy week         < pregnancy week
 HCG                                >50,000 mini IU/ml       <50,000 mini IU/ml
Thecalutein cyst                 Present                           Absent 
Clinical manifestation :
  • Abdomen pain
  •  Red and brown veginal discharge 
  •  Pain veginal bleeding 
  •  Expulsion of grape like structure
  •  Complication :- Coriocarcinoma
Rx :- Suction and evacuation 
NSG :- Advise the mother to conceive within 1 year
2. Ectopic pregnancy:
  • Implantation does not occur at the anterior or posterior wall of the fundus of the uterus.
  •  Common site : Tubal pregnancy; mostly ampulla. 
  • Before 12 weeks: colicky pain, Vaginal bleeding (Placental ;Ist trimester bleeding ) 
  •  Syncope loss of conscious if tube rupture
  •  Vaginal Spotting to bleeding Dark red or brown).
          Methotrexate (Folic acid antagonist) is given to Inhibit cell division in embryo 

3.Abortion
  • Bleeding per vagina before 20 weeks of gestation. 
  • Spontaneous
 Methods of abortion :
1. Chemical method : Mafepristone, PGE 
2. Vacuum
3. D & E/C
Type of abortion :
1. Complete abortion : Complete product expells from uterus 
  •  C/M :- Subside pain 
  • Absent vaginal bleeding 
  • close the cervical oss
2.  Incomplete abortion : Some part of conception retains in to uterus, while most of the part expelled 
  • Vaginal bleeding present
  • Pain in lower abdomen
 3. Missed abortion (Silent abortion) :- Death of fetus in uterus
  •  Brown colour vaginal bleeding.
  • Absent of S/S of pregnancy 

4. Threatened abortion :
  •  Continuous of pregnancy is possible
  • Painless slightly bleeding
  • Dull nature abdominal pain 
  • can be prevented by active management

5. Inevitable abortion-abortion occurs after active management 
  • Increase amount of vaginal bleeding
  •  Painful red colour bleeding
  •  Pain in lower abdomen 
6. Septic abortion :- Due to infection 
  • After 24 hours increasing body temperature
  • Offensive vaginal discharge
 7. Recurrent/Habitual abortion :- > 3 time spontinous abortion 


Late Bleeding in pregnancy
 Bleeding after 28 weeks of gestation, 
1. - Placenta Previa- Placenta Implant at lower uterus :
 I. Low lying, level-1:- Only marginal part attach to lower uterine segment 
II. Marginal , level-2  - Placenta comes in touch of margins of internal oss
 III. Incomplete, level-3  - Placenta cover internal oss than its close but partly cover vein it diluted
 IV. Complete, Level-4 .- Placenta cover internal oss completely even after dilation
  • Most Severe-Posterior marginal (Level-2, Posterior)

C/M- Sudden recurrent painless bright red colour  bleeding 
• Stallworthy's sign -down Fetal heart rate during compression of fetal head into pelvis

 NSG :-Never attempt vaginal examination
            Position - Left lateral /Semifowlers
            Complete bed rest
 2. Abruptio Placenta - Immature Separation of placenta. 
Three types 
:I. Revealed - Bleeding externally visible (most common abruptio placenta)
 II. Concealed :- Bleeding externally not visible (most dangerous condition)
 III. Mixed :- Sub blood loss externally visible and some blood internally accumulation
 
  • CM:-  Dark red colour painful vaginal bleeding
  •            Tender uterus
  •              Position - Trandleburg position
  •               Fibrine knot's present in hepatic sinusoids
  •              Provide trendelenburg position to avoid fetal compression by placenta
   Q.   A Mother at 32 weeks of gestation comes to casualty with severe abdominal pain with dark                                                           per vaginal bleeding, most accurate position given by a nurse
    Ans. Trendelenburg position 

Postpartum Haemorrhage :    Blood loss > 500 ml after delivery, so cause a condition that leads decrease BP and Hypovolemic shock 
  • C/M:-1st sign - tachycardia
  • late sign - hypotension 
  • Causes-Multigravida
  • Atonicity of uterus-most common cause: oxytocin should be given to increase uterine contraction 
  • Primary PPH: Start within 30 minutes after placental expulsion. 
  • Traumatic PPH:
  • Secondary PPH:-due to infection

Management -
  •         Vaginal packing
  •          Uterine artery ligation
 Endometritis:
  •         Infection of uterine lining in Postpartum period. 
  •          Caused by bacteria Invade the uterus
  •            Infection may cause peritonitis or pelvic thrombophlebitis 
S/S -- Chills, fever,
           Tender, large uterus,
            Foul odour of lochia or reddish brown lochia,
 Position:
          Fowler's to facilitate drainage of lochia.

 Disorders during pregnancy 
  •          PIH
  •           Hydramnios
  •          Precipitated v/s prolonged labour
  •          D.M.
       
 DIC :- Disseminated Intravascular coagulation.

           Clotting cascade activate, Intravascular clot formation

           platelet & clotting factor.

           Bleeding/Vascular occlusion Thrombɔemboli formation in blood.

 C/M :- Bleeding, 
             Renal failure (Complication) of DIC - So check  for urine output (should not less than 30 ml/hr) 
        
 Pregnancy induced hypertension (PIH)
           
1. Preeclampsia :
  • increased BP
  •  Proteinuria - Late appearance 
  • B.P. Oedema Proteinuria 
  • Ankle Oedema-Early morning appearance 
  • Headache - Vision disturbance
  • Oligurie 
  • Indigestion :- Serum uric acid-> 4.5 mg per day) 

2. Eclampsia :-Preeclampsia + seizures, B.P. 140/90 MmHg 
  • Drug of choice : Mgso4 (Dose=4-6 gm/4hour) 
  • The normal therapeutic level of MgSo, in blood -4-7 meq/liter 
  • Action: management of fits
  • · Antidot : Calcium gluconate  (10ml:10mg:10minute)
HELLP Syndrome of PIH
  • H - Haemolysis
  •  EL - Elevated liver Enzyme
  • LP-Low platelets 

Complication of MgSo4
  • decres Deep tendon reflex
  •  Respiratory depression 
  • Cardiac arrest 
 Priority action after seizure episode - 
  • Maintaining airway- (Suction) Suctioning should be done at first mouth than nose 
  • During Seizure mouth gag should not used 
  • Restraint should not used during seizure episode
Hydramnios
  • Oligohydramnios- <200 ml at term 
  • Polyhydramnios >2000ml 

Diabetes Mellitus :Gestational DM :
  •  In II & III trimester placental hormones cause Insulin resistant state, requiring an increased Insulin dose. 
  • Fetus produce Insulin & take glucose from mother, with predispose mother for hypoglycemic 
  • Newborn- Macrosomic. 
  • At Risk- Hypoglycemia, Hyperbilirubinemia, RDS, hypocalcemia, Congenital anomalies. 
  • Oral hypoglycemic agents are never given during pregnancy. 
  •  Baby becomes macrosomic (larger than normal) & Hypoglycemic 
Q.: Safe period for X-ray in tuberculosis to pregnant mother Ans. After 20 weeks 
  • Safest drug :1. Isoniazid
  • Side effect :- Peripheral, neuritis, to prevent neuritis VitB6 (pyridoxine) should be given 
  • HIV: - Give zidovudine to pregnant women after 14
  • week's gestation to prevent maternal to fetal transmission 
  •  During labour - Give IV. 
  •  In the form of Synup to newborn for 6 weeks after birth.
 Test: 
  • ELISA, Western blot & Immunofluorescenceassay (IFA)
  • Confirmatory test (Reform after ELISA is +ve) 
  • Q.: Highest Risk of HIV transmission is-  During Intrapartum period - Through birth canal
  •  
  • All newborn of HIV +ve mother having HIV +ve antibodies from mother but not necessary Infection.
  • Up to 18 month antibodies persist in the newborn. 
  •  HIV +ve mother-Give bottle feeding to newborn Infant
  •  Newborn of HIV +ve mother :
Intervention :
  • (1) Give zidovudine upto 6 week. (Syrup from). 
  • (2) Bath neonate before Invasive procedure. 
  • (3) At risk for Pneumocystis Jiroveci/Carinii Infection.
  •  (4) Live vaccine not administered & scheduled to follow properly. 
During Labour :
  •  Maximum chances of spread of HIV from mother to fetus.
  •  HIV Virus :- Retrovirus 
  •  During breastfeeding-HIV may be transmit into newborn  
  • Maximum chance of HIV transmission from mother to child is Breast feed + supplementary food given
  •   Chances are very less if exclusive breast feeding is given, because mother's milk make protective layer against virus in child's GIT 
  • Screening of AIDS-ELISA Test
  •  Confirmation test Western blot test

Anaemia  
  • criteria of anaemia < 10 gm/100 ml/dl 
  • Physiological anaemia- due to haemodilution; fluid increases in pregnancy (2.5-3 litre) 
  • Anemia :-Hb10gm/dl & hematocrit < 30%. 
  • Take Iron + Vit C & citric fruit to increase  absorption.
  • Avoid Iron intake of tea & milk.
  •  Folic acid supplement is given in A trimester bocz organogenesis occurs in this.  Iron supplements  given in II trimester bocz due to vomiting, Not absorbed in 1st trimester. 
Rh incompatibility
  • If mother Rh Negative Fetus: Rh Positive 
  •  Ilnd baby is at more risk
  • Give Anti-D Immunoglobulin; Doses:befor 12wk 50 mg Rout: IM
  • Time: within 72 hrs, after delivery or be After 12 weeks of gestation: 300 mg (within three dose) given 
Tocolytic drugs :- Uterine relaxants
  • It is given in case of precipitated & Pre term labour 
  • Eg. salbutamol
 Lecithin Sphingomyelin ratio at term: > 2:1 Indicate Lung Maturity 
  • Corticosteroids (Betamethasone)- Given to Mother to make lung mature 
  • Also give to baby after birth (Instill in trachea) 
In cord prolapse:
1. Modified Sim's Position 2. Knee-Chest Position 3. Trendelenburg Position 
Episiotomy :
  • Commonest; Mediolateral 
  • Sitz bath should be given (105-1109) F-after 24hours 
  •  If hematoma form in episiotomy: Ist 24 hour-Cold application (Ice pack)
  • After 24 hour-hot application

After delivery up to 24 hours bradycardia & hyperthermia is common findings.
 Within 24 hr delivery - Hyperpyrexia (100.4°F)
 Delivery BradyCardia (50-80) 
Q.: A Peurpera's pulse is 55 bpm, 2 hrs after delivery what a nurse should do
 Ans: It is considered as normal, watch constantly
Puerperal Pyrexia
  • 24 hrs-10 day after delivery
  • Puerperal sepsis-infection is the common cause 
Leg cramps in pregnancy-
  •  Due to altered calcium-Phosphorus balance & presser of the uterus on the nerve. 
  • Management : (1) increase Ca+ & vit D intake. 
Kick Counts:
  • Counted inside the lying position. 
  • Place Mother hand on fundus. 
  • 10 kicks in 12 hours is normal, If below notify Physician
 Drugs Use in pregnancy :
Tocolytic
  • Function - Decrease uterine contraction
  •  Use in preterm labour
  • Don't use after 37 week of pregnancy
 (A) Prostaglandin inhibitor - Indomethacin 50 mg oral
→ Prevention for preterm labour 
 (B) MgSO4, Use - Eclampsia and preterm labour
 (C)Nifedipine/Amlodipine - Calcium channel blocker
  • Antihypertensive drug → Dose - 10-20 mg/4 hours
(D) Terbutaline - It is bronchodilator
  •  Decrease contraction
  • It is a antidote of oxytocin
  • Dosc- .25mg slc infiction Q4H 
2. Anticonvulsant drug :(A) MgSO4; (B) Diazepam - 20-40 mg/IV. (C) Phenytoin - 10 mg/kg/body weight 
3. Anticoagulants
(A) Heparin- Route - SIC Dose - 5000-10000 IU.IV
  • Antidote - Protamine sulphate 
(B) Warfarin :- Dosel- 10 mg oral
Antidote - Vitamin-K
  Conradi syndrome-Warfarin toxicity to fetus- Facial and skeletal abnormality 
4. Antihypertensive drug :
(A) Methyldopa - 250mg, first choice of drug
  • Contraindication in puerperium, it cause depression 
(B) Labetalol- 100 mg 
C) Nifedipine-10-20mg 
(D) Sodium nitro fruside - only use hypertensive crisis 
(E) ACE- Inhibitor - Captopril (6.25 mg)
  •  It should be avoided in pregnancy after 12 week and before crowning of head because it cause fetal renal failure 
5. Oxytocics drug :
  • Increase uterine contraction 
(A) Oxitocina/Pitocin :Does - 10 IU 
  • Uses - MTP,Abortion Expulsion of vesicullar mole, stop bleeding after D&C Induction of labour 
(B) Ergot derivatives
  • Ergometrin - It should not use in induction of labour and abortion, it cause utrine spasm 
  • Methergine - don't use in preeclampsia and eclampsia 
6. Mendelson's syndrome. It is a complication of general anesthesia

* Galactogogues drug - increase milk production
MCP,  Sulphurmide, Domperidon
 * bromocriptine- Milk suppercent 

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